Publications by Mr John Watkinson

The Management of Squamous Cell Carcinoma of the Neck. The Birmingham UK Experience.

Watkinson JC, Mastronikolis NS, Fitzgerald D, Owen C, Neary Z & Glaholm J.
EJSO April 2005

Is Clinical Otolaryngology publishing patient-centred research?

Bem, C, Lee, C, Dawson, R and Watkinson, JC 2004.
Clin Otolaryngol 29:84-93

Adenoviral delivery of dominant negative fibroblast growth factor receptor 1 blocks FGF effects in thyroid cells and reduces goitrogenesis in mice.

EL Davies, *JD Ramsden, **H Cocks, P Searle, J Watkinson, 1H Ueno, A Logan, JA Franklyn, V Mautner, MC Eggo. 2003.
Journal of Clinical Endocrinology and Metabolism 88:4472-4480

Characterisation of a strain of human thyroid endothelial cells and its interactions with thyroid follicular cells.

Patel V, Logan A, Watkinson JC, Zaman S Uz, Sheppard MC, Ramsden J, Eggo MC.
Am J Physiol 2003. 284 E168-176

Role and regulation of the fibroblast growth factor axis in human thyroid follicular cells.

Cocks H, Thompson S, Turner FE, Logan A, Franklyn JA, Watkinson JC, Eggo MC.
Am J Physiol 2003. 285 E460-469

Adenoviral delivery of dominant negative fibroblast growth factor receptor 1 blocks FGF effects in thyroid cells and reduces goitrogenesis in mice.

Davies EL, Ramsden JD, Cocks H, Turner F, Searle P, Watkinson JC, Ueno H, Logan A, Franklyn JA, Mautner V, Eggo MC.
J Clin Endocrinol Metab. 2003. 88:4472-4480

Isolation and characterization of human thyroid cells in vitro.

Patel VA, Logan A, Watkinson JC, Uz-Zaman S, Sheppard MC, Ramsden JD, Eggo MC 2003.
J Clin Endocrinol Metab 82:2702-9

Conservation Surgery in the Management of T1 and T2 Oropharyngeal Squamous Cell Carcinoma: The Birmingham UK Experience.

Watkinson JC, Thompson S, Owen C, Das Gupta AR, Glaholm J.
Clin Otolaryngol. 2002 27, p541-548.

Who Performs Thyroid Surgery – A Review of Current Otolaryngological Practice.

Ramsden JD, Johnson AP, Cocks HC, Watkinson JC.
Clin. Otolaryngol. 2002. 27, p310-313.

Thyroid follicular cells secrete plasminogen activators and can form angiostatin from plasminogen.

Ramsden JD, Yarram S, Matthews E, Watkinson JC, Eggo MC.
J Endocrinol 2002. 173:475-81

An audit of management of differentiated thyroid cancer in specialist and non-specialist clinic settings.

Kumar H, Daykin J, Holder R, Watkinson JC, Sheppard MC and Franklyn JA.
Clin. Endocrinol. 2001 54, 719-723.

Tie 2 is expressed on thyroid follicular cells, is increased in goiter and is regulated by thyrotropin through cyclic adenosine 3’5’-monophosphate.

Ramsden JD, Cocks HC, Shams M, Nijjar S, Watkinson JC, Sheppard MC, Ahmed A, Eggo MC.
J Clin Endocrinol Metab. 2001 Jun;86(6):2709-16.

Thyroid stimulating hormone increased angiogenic growth factor expression in rat thyrocytes.

Cocks HC, Ramsden JD, Watkinson JC, Eggo MC.
Clin Otolaryngol. 2000 Dec;25(6):570-6

Patients’ Preferences in Psychosocial Support on a Head and Neck Oncology Unit.

Owen C, Watkinson JC, and Harrison S.
Psycho-oncology. 2000

Reconstructive techniques currently used following resection of hypopharyngeal carcinoma.

Ayshford CA, Walsh RM, Watkinson JC;
J Laryngol Otol. 1999 Feb;113(2):145-8.

Gender, Clinical Findings, and Serum Thyrotropin Measurements in the Prediction of Thyroid Neoplasia in 1005 Patients Presenting With Thyroid Enlargement and Investigated by Fine-Needle Aspiration Cytology.

Kumar H, Daykin J, Holder R, Watkinson JC, Sheppard MC, and Franklyn JA.
Thyroid, Vol 9. 1999 Thyroid. 11: 1105-1109

Allelic deletion at 8p11.2 is a frequent event in head and neck cancer and identifiable using FISH on tumour imprints.

Kuo MJ, Crundwell MC, Knowles M, Oates J, Watkinson JC, Warfield AT, Morton DG, Neoptolemos JP.
British Journal of Surgery. 1998 85: 1563.

Frequent loss of 5q21 in head and neck cancer without inactivation of the APC gene implies the presence of another putative tumour suppressor gene at 5q21.

Kuo MJ, Mackay SJ, Oates J, Warfield AT, Watkinson JC, Morton DG, Neoptolemos JP.
British Journal of Surgery. 1998 85: 1575.

Fibroblast growth factors 1 and 2 and fibroblast growth factor receptor 1 are elevated in thyroid hyperplasia.

Thompson SD, Franklyn JA*, Watkinson JC*, Verhaeg JM, Sheppard MC*, Eggo MC*.
Journal of Clinical Endocrinology and Metabolism 1998;83 (4): 1336-1341

An audit of one surgeon’s experience of oral squamous cell carcinoma using a computerised malignancy database.

Watkinson JC
Ann R Coll Surg Engl. 1996 Sep;78(5):479-80.

Oncocytic carcinoma of the parotid gland: a problem in fine needle aspiration diagnosis.

Harrison RF, Smallman LA, Young JA, Watkinson JC.
Cytopathology. 1995 Feb;6(1):54-8

Travelling Fellowship Report.

Watkinson JC.
Annals of The Royal College of Surgeons of England 1993.

Travelling Fellowship Report.

Watkinson JC.
Nucl. Med. Commun. 1993.

Metastatic Squamous Carcinoma of the Head and Neck: An Anatomical and Physiological Study using CT and SPECT TC99m (v) DMSA.

Watkinson JC, Lazarus CR, Todd C, Maisey MN and Clarke SEM.
Br. J. Radiol. 1991 64, p909-914.

The Pharmacokinetics and Biodistribution of TC99m (v) DMSA in an Animal Tumour Model.

Watkinson JC, Allen S, Laws D, Lazarus CR, Maisey MN and Clarke SEM.
J. Nucl. Med. 1991 32, p1235-1238.

Free Flaps in Head and neck Reconstructive Surgery: A Review of 79 Cases.

Watkinson JC, and Breach NM.
Clin. Otolaryngol. 1991 16, p350-353.

Metastatic Carcinoma in the Neck: A Clinical, Radiological Scintigraphic and Pathological Study.

Watkinson JC, Todd CEC, Paskin L, Rankin S, Palmer T, Shaheen OH, and Clarke SEM.
Clin. Otolaryngol. 1991 16, p187-192.

The Surgical Management of Medullary Carcinoma of the Thyroid.

Lannigan F, Watkinson JC, Clarke SEM and Shaheen OH.
Ann. R. Coll. Surg. Engl. 1991 73, p27-31.

A Clinical and Scintigraphic Study in an Animal Tumour Model.

Watkinson JC, Allen S, Lazarus CR, Laws D, Hibbert J and Clarke SEM. TC99m (v) DMSA:
Clin. Otolaryngol. 1990 15, p497-501.

TC99m (v) DMSA Planar Scintigraphy in Head and Neck Cancer: A Clinical, Scintigraphic and Radiological Study.

Watkinson JC, Todd CEC, Lazarus CR, Maisey MN and Clarke SEM.
J. Laryngol. Otol. 1990 104, p783-789.

The Reliability of Palpation in the Assessment of Tumours.

Watkinson JC, Johnston D, Jones N, Coady M, Laws D, Allen S and Hibbert J.
Clin. Otolaryngol. 1990 15, p405-409.

The Subcellular Biodistribution of TC99m (v) DMSA in Squamous Carcinoma. A Comparative Study in Humans and in Animal Tumour Model.

Watkinson JC, Allen S, Higgins M, Bharij A, Lazarus CR, Maisey MN and Clarke SEM.
Nucl. Med. Commun. 1990 11, p547-555.

The Pharmocokinetics and Biodistribution of TC99m (v) DMSA in Humans with Squamous Cell Carcinoma.

Watkinson JC, Allen S, Lazarus CR, Sinclair J, Black G and Clarke SEM.
Nucl. Med. Commun. 1990 11, p343-359.

TC99m (v) DMSA: The Pituitary Sign.

Watkinson JC, Lazarus CR, Maisey MN and Clarke SEM.
Nucl. Med. Commun. 1990 11, p313-317.

TC99m (v) DMSA: A Clinical, Planar and SPECT Study to Evaluate Patients with Head and Neck Squamous Carcinoma.

Watkinson JC, Lazarus CR, Mistry R, Maisey MN and Clarke SEM.
Nucl. Med. Commun. 1990 11, p111-1120.

TC99m (v) DMSA and Gallium-67 Citrate Imaging in Patients with Head and Neck Squamous Cell Carcinoma.

Watkinson JC, Lazarus CR, Maisey MN and Clarke SEM.
Nucl. Med. Commun. 1990 11, p103-110.

TC99m (v) DMSA Planar Scintigraphy - Does it have a Role in the Management of patients with Head and Neck Squamous Carcinoma?

Watkinson JC, Lazarus CR, Maisey MN and Clarke SEM.
Nucl. Med. Commun. 1989 100, p859-870.

What is the Optimal Imaging Time for TC99m (v) DMSA Planar Scintigraphy in the Detection of Squamous Carcinoma? A Comparable Study Humans and in an Animal Tumour Model.

Watkinson JC, Allen S, Lazarus C, Maisey MN and Clarke SEM.
Nucl. Med. Commun. 1989 10, p741-750.

TC99m (v) DMSA Uptake in Patients with Head and Neck Squamous Cell Carcinoma - Experience in Imaging.

Watkinson JC, Lazarus CR, Mistry R, Shaheen OH, Maisey MN and Clarke SEM.
J. Nucl. Med. 1989 30, P174-180.

An Evaluation of the Uptake of TC99m (v) DMSA in Patients with Squamous Cell carcinoma of the Head and Neck.

Watkinson JC, Clarke SEM and Shaheen OH.
Clin. Otolaryngol. 1987 12, p405-41.

Books

Head and Neck Surgery 4th edition.

Stell & Maran, Editors Watkinson J.C, Gaze, M and Wilson.
J. Butterworth Heinemann 2000.

Booklets

BACUP 2003

1. Understanding Cancer of the Thyroid
2. Understanding Cancers of the Head & Neck

Chapters

Fundamental Principles of Nuclear Medicine in Otolaryngology.

Watkinson JC
In Scott Brown's Otolaryngology. 6th ed. Volume 1 (Basic Sciences), 1997 Butterworth Heinemann

Epistaxis

Watkinson, JC.
In Scott Brown's Otolaryngology. 6th ed. Rhinology Volume, 1997

Surgery of the Parotid Gland, 1998.

Watkinson JC.
In Operative Otorhinolaryngology. Blackwell Science p 436-443

The Management of Thyroid Tumours.

Watkinson JC.
Disorders of the Head and Neck, Nose and Throat. Arnold 1998, p 347-370

Surgical Anatomy of the Head and Neck.

Sharp J and Watkinson JC.
Disorders of the Head and Neck, Nose and Throat. Arnold 1998, p 11-23

Chapter: Thyroid Disease – Benign.

Watkinson JC.
Key Topics in Otolaryngology Second Edition. 2001 BIOS Scientific Publishers Ltd.

Chapter: Thyroid Disease – Malignant.

Watkinson JC.
Key Topics in Otolaryngology Second Edition. 2001 BIOS Scientific Publishers Ltd.

Reviews

Oncogenes in Thyroid Cancer.

Kim, DS, McCabe, CJ, Buchanan MA & Watkinson, JC.
Clin. Otolaryngol 2003 28: p386-395.

Gene Chip expression analysis in Head & Neck Cancer.

Kim DS and Watkinson JC.
Clin. Otolaryngol. 2002. 27, 296-303.

Carcinoma of the nasopharynx. A review.

McDermott A and Dutt S and Watkinson JC.
Clin. Otolaryngol. 2001. 26, 82-92.

The management of the solitary thyroid nodule. A review.

Walsh, R and Watkinson, J C and Franklyn, J.
Clin. Otolaryngol. 1999. 24, 388-397.

Nuclear Medicine in Otolaryngology: A Review.

Watkinson, JC.
Clin. Otolaryngol. 1990 15, p457-69.

Imaging Head and Neck Cancer with Radioisotopes. A Review.

Watkinson, JC, Maisey, MN.
JRSM 1988 81, p653-657.

Editorials

The COG Guidelines for Head & Neck Cancer.

Watkinson, JC and Haward, R.
ENT News 2003.

The Psychosocial Impact of Head and Neck Cancer.

Owen C, Watkinson J C, Pracy P, Glaholm J.
J. Clin Otolaryngol 2001.

Developments in Radiotherapy and Adjuvant Chemotherapy for Head and Neck Cancer.

Glaholm, J. and Watkinson, JC.
Clin Otolaryngol 2003, 28, 1-4

The Treatment of Head & Neck Cancer: The Calman-Hine Proposals.

Watkinson, JC.
ENT News, Vol 7, No. 4. P11-12.

The Clinically No Neck: Investigation and Treatment.

Watkinson, JC.
Clin. Otolaryngol. 1993 18, p443-445.

Conservation surgery in Head and Neck Cancer.

Shepherd I, Watkinson JC and Glaholm.
J. Clin Otolaryngol 1998. 23. p385-387.

TC99m (v) DMSA - What is its Current Role in the Management of Patients with Head and Neck Cancer?

Watkinson, JC.
Current Opinion in Radiology, February 1992.

Nuclear Medicine in Otolaryngology.

Watkinson, JC.
Nucl. Med. Commun. 1992 12, p1001-1005.

TC99m (v) DMSA: What is its Current Role in the Management of Patients with Head and Neck Cancer?

Watkinson, JC, Clarke, SEM.
Nucl. Med. Commun. 1991 12, p79-82.

The Evaluation of the Solitary Thyroid Nodule.

Watkinson, JC.
Clin. Otolaryngol. 1990 15, p1-5.